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It is used in the automotive and aeronautical industry to make fuel and oil handling hoses, seals, grommets, and self-sealing fuel tanks, since ordinary rubbers cannot be used. It is used in the nuclear industry to make protective gloves. NBR's ability to withstand a range of temperatures from −40 to 108 °C (−40 to 226 °F) makes it an ideal material for aeronautical applications. Nitrile butadiene is also used to create moulded goods, footwear, adhesives, sealants, sponges, expanded foams, and floor mats.
Nitrile sheets are use in cold insulation too.